Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27150696 | 0.92 | ACKR3 (0.41) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL1118133 | 0.85 | LMNA (0.52) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL5233223 | 0.81 | LMNA (0.48) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL30846066 | 0.79 | CKS1B (0.40) | LMNAOGAABCB1ACKR3MEN1 | |
| SCHEMBL30807303 | 0.79 | MAP4K4 (0.40) | OGAHRH3ACKR3NR1H2NR1H3 | |
| SCHEMBL30807235 | 0.79 | MAP4K4 (0.40) | OGAHRH3ACKR3NR1H2NR1H3 | |
| SCHEMBL15349119 | 0.78 | HRH3 (0.58) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL27147155 | 0.78 | HRH3 (0.35) | LMNAMAPTSMN1; SMN2MAPK1OGA | |
| SCHEMBL30807243 | 0.78 | HRH3 (0.32) | HRH3ACKR3 | |
| SCHEMBL27152090 | 0.77 | ACACB (0.38) | LMNAMAPTSMN1; SMN2TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577211-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | Wake Forest University Health Sciences (US) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024044744-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2024-02-29 | — | — | WO | disclosed |