Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | OGA | O60502 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 2/20 | 0.46 |
| ▸ | SKP1 | P63208 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1118133 | 0.96 | LMNA (0.52) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL16836625 | 0.88 | HRH3 (0.56) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL5231570 | 0.86 | CKS1B (0.47) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL15349119 | 0.83 | HRH3 (0.58) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL5231938 | 0.83 | CKS1B (0.48) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL7185606 | 0.83 | ALDH1A1 (0.62) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL10464669 | 0.82 | ALDH1A1 (0.64) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL30686624 | 0.82 | OGA (0.44) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL30807271 | 0.81 | LMNA (0.40) | LMNAMAPTSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL13129749 | 0.81 | CKS1B (0.46) | LMNAMAPTSMN1; SMN2TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |