SCHEMBL30807337

SCHEMBL30807337

COCCOCC(=O)N1CCN(c2nc(C(=O)N[C@@H](CO[Si](C)(C)C(C)(C)C)C(=O)OC)cs2)CC1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OGA O60502 3/20 0.37
PIN1 Q13526 3/20 0.34
P2RY12 Q9H244 1/20 0.34
HRH3 Q9Y5N1 2/20 0.34
KMT2A Q03164 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
EPHX2 P34913 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31364452 0.93 OGA (0.35) OGAPIN1P2RY12HRH3KMT2A
SCHEMBL27151799 0.87 OGA (0.40) OGAPIN1P2RY12HRH3KMT2A
SCHEMBL27151800 0.87 OGA (0.40) OGAPIN1P2RY12HRH3KMT2A
SCHEMBL30807239 0.87 ACKR3 (0.41) OGAP2RY12HRH3KMT2A
SCHEMBL27153913 0.86 ACKR3 (0.36) OGAPIN1HRH3KMT2A
SCHEMBL27143881 0.86 ACKR3 (0.36) OGAPIN1HRH3KMT2A
SCHEMBL27145073 0.85 HRH3 (0.33) OGAP2RY12HRH3KMT2A
SCHEMBL31364459 0.84 KMT2A (0.44) KMT2A
SCHEMBL27153217 0.83 ACKR3 (0.37) OGAPIN1P2RY12HRH3KMT2A
SCHEMBL30807308 0.82 PIN1 (0.43) OGAPIN1P2RY12HRH3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062407-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER UNIV WAKE FOREST HEALTH SCIENCES (US) 2026-03-05 US disclosed
US-20250381278-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER UNIV WAKE FOREST HEALTH SCIENCES (US) 2025-12-18 US disclosed
EP-4577211-A2 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER Wake Forest University Health Sciences (US) 2025-07-02 EP disclosed
US-20250011316-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES 2025-01-09 US disclosed
WO-2024044744-A2 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2024-02-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062407-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER PRDX1, PRDX3, PRDX2 OGA 3488/4885PIN1 3679/4885P2RY12 2220/4885
US-20250011316-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER PRDX1, PRDX2, PRDX6 OGA 2739/4885PIN1 1552/4885P2RY12 1416/4885
US-20250381278-A1 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER PRDX1, PRDX2, PRDX6 OGA 2664/4885PIN1 1487/4885P2RY12 1440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.