Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27138888 | 1.00 | PDK1 (0.47) | PDK1LIMK1POLBCDK2FLT3 | |
| SCHEMBL31132475 | 0.84 | JAK2 (0.35) | PDK1ALDH1A1 | |
| SCHEMBL16963100 | 0.77 | PDK1 (0.39) | PDK1 | |
| SCHEMBL16759894 | 0.77 | PDK1 (0.39) | PDK1 | |
| SCHEMBL8482514 | 0.77 | PDK1 (0.46) | PDK1LIMK1CDK2FLT3CCNA1 | |
| SCHEMBL1417741 | 0.74 | DRD2 (0.48) | PDK1LIMK1CDK2FLT3CCNA1 | |
| SCHEMBL19644337 | 0.73 | PDK1 (0.43) | PDK1LIMK1POLBCDK2FLT3 | |
| SCHEMBL8482518 | 0.71 | PDK1 (0.49) | PDK1LIMK1ALDH1A1 | |
| SCHEMBL4441055 | 0.71 | PDK1 (0.52) | PDK1LIMK1ALDH1A1MAPT | |
| SCHEMBL14328268 | 0.71 | PDK1 (0.50) | PDK1LIMK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043741-A1 | AUTOTAXIN INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 레고켐 바이오사이언스 | 2024-02-29 | — | — | WO | disclosed |