Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 2/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27145036 | 1.00 | NR3C1 (0.39) | NR3C1PGRNR3C2EPHX1MAPT | |
| SCHEMBL27145035 | 1.00 | NR3C1 (0.39) | NR3C1PGRNR3C2EPHX1MAPT | |
| SCHEMBL31092589 | 0.97 | NR3C1 (0.40) | NR3C1PGRNR3C2EPHX1MAPT | |
| SCHEMBL30807690 | 0.88 | NR3C1 (0.37) | NR3C1PGRNR3C2MAPTTP53 | |
| SCHEMBL27154529 | 0.88 | NR3C1 (0.37) | NR3C1PGRNR3C2MAPTTP53 | |
| SCHEMBL27154530 | 0.88 | NR3C1 (0.37) | NR3C1PGRNR3C2MAPTTP53 | |
| SCHEMBL30807621 | 0.85 | NR3C1 (0.38) | NR3C1PGRNR3C2GPR27SCN1A | |
| SCHEMBL31092623 | 0.85 | NR3C1 (0.38) | NR3C1PGRNR3C2GPR27SCN1A | |
| SCHEMBL27146021 | 0.85 | NR3C1 (0.38) | NR3C1PGRNR3C2GPR27SCN1A | |
| SCHEMBL27146019 | 0.85 | NR3C1 (0.38) | NR3C1PGRNR3C2GPR27SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044183-A1 | FUSED HETEROBICYCLIC ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |