Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27139452 | 1.00 | ALOX5AP (0.48) | ALOX5APFEN1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL27139455 | 1.00 | ALOX5AP (0.48) | ALOX5APFEN1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL27148826 | 0.89 | ALDH1A1 (0.55) | ALOX5APFEN1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL30807823 | 0.83 | AAK1 (0.42) | ALOX5APFEN1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL15917052 | 0.78 | POLB (0.55) | ALOX5APFEN1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL3023376 | 0.70 | NR3C1 (0.51) | ALDH1A1KDM4ESLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16886882 | 0.70 | CA1 (0.39) | ALOX5APFEN1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL3247810 | 0.70 | CA1 (0.39) | ALOX5APFEN1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL16886883 | 0.70 | CA1 (0.39) | ALOX5APFEN1CYP2C19ALDH1A1KDM4E | |
| SCHEMBL3196118 | 0.69 | NR3C1 (0.47) | ALOX5APFEN1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044183-A1 | FUSED HETEROBICYCLIC ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |