Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29209282 | 1.00 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL30114794 | 0.85 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL28691325 | 0.73 | KDM4E (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10215145 | 0.71 | ALDH1A1 (0.57) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL28107900 | 0.71 | MAPT (0.41) | MEN1KMT2AMAPTSMN1; SMN2CYP19A1 | |
| SCHEMBL27620339 | 0.69 | MAPT (0.42) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL3824986 | 0.69 | MAPT (0.42) | MEN1KMT2AMAPTSMN1; SMN2CYP19A1 | |
| SCHEMBL7662705 | 0.69 | KMT2A (0.79) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8740607 | 0.68 | DAO (0.61) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL11488198 | 0.68 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715900-A | SRPK inhibitors | 默克专利股份公司 | 2024-03-15 | — | — | CN | disclosed |