Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.61 |
| ▸ | F7 | P08709 | 2/20 | 0.56 |
| ▸ | F3 | P13726 | 2/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | F11 | P03951 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17022664 | 0.83 | DAO (0.61) | DAOF7F3F11ALDH1A1 | |
| SCHEMBL2454392 | 0.77 | FLT3 (0.59) | HRH4FLT3 | |
| SCHEMBL27437661 | 0.77 | LOXL2 (0.57) | DAOF7F3LOXL2F11 | |
| SCHEMBL32666155 | 0.77 | FLT3 (0.59) | HRH4FLT3 | |
| SCHEMBL16767857 | 0.76 | DAO (1.00) | DAOF7F3F11SIRT1 | |
| SCHEMBL10215145 | 0.75 | ALDH1A1 (0.57) | DAOF7F3LOXL2F11 | |
| SCHEMBL9852611 | 0.74 | DAO (0.61) | DAOLOXL2MEN1KMT2ANPC1 | |
| SCHEMBL18850955 | 0.74 | LOXL2 (0.53) | DAOF7F3LOXL2F11 | |
| SCHEMBL11436421 | 0.74 | DAO (0.61) | DAOALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL1465978 | 0.74 | LOXL2 (0.58) | DAOF7F3LOXL2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7196610-A | — | — | None | — | — | JP | disclosed |
| WO-2023246876-A1 | MEDICAL USE OF FORMAMIDE DERIVATIVES, FORMAMIDE DERIVATIVES, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 上海科技大学 | 2023-12-28 | — | — | WO | disclosed |
| CN-106170489-B | New Pyrazolopyrimidine derivative and its purposes as MALT1 inhibitor | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-106170489-A | New Pyrazolopyrimidine derivative and the purposes as MALT1 inhibitor thereof | 诺华股份有限公司 | 2016-11-30 | — | — | CN | disclosed |
| CN-102702068-B | 3-pyrrolo-cyclohexylidene-2-dihydroindolone derivative, and application of 3-pyrrolo-cyclohexylidene-2-dihydroindolone derivative | NANJING YOKO BIOLOG PHARMACEUTICAL RES CO LTD | 2014-05-14 | — | — | CN | disclosed |
| CN-101300259-B | Tricyclic spiro derivatives as CRTH2 modulators | MERCK SERONO SA | 2013-08-28 | — | — | CN | disclosed |
| CN-101389624-B | 3-pyrrolocyclohexylidene-2-indolinone derivative and application thereof | JIANGSU SIMCERE PHARM RES CO | 2012-10-03 | — | — | CN | disclosed |
| CN-102702068-A | 3-pyrrolo-cyclohexylidene-2-dihydroindolone derivative, and application of 3-pyrrolo-cyclohexylidene-2-dihydroindolone derivative | JIANGSU SIMCERE PHARM RES CO | 2012-10-03 | — | — | CN | disclosed |
| CN-100564375-C | (3Z) -3- (2, 3-dihydro-1H-inden-1-ylidene) -1, 3-dihydro-2H-indol-2-ones as kinase inhibitors | ALLERGAN INC (US) | 2009-12-02 | — | — | CN | disclosed |
| CN-101300259-A | Tricyclic spiro derivatives as CRTH2 modulators | SERONO LAB (CH) | 2008-11-05 | — | — | CN | disclosed |
| WO-1995020574-A1 | PROCESS FOR PREPARING 2-OXINDOLE-1-CARBOXAMIDES | CATALYTICA, INC. (US) | 1995-08-03 | — | — | WO | disclosed |
| JP-H07196610-A | PRODUCTION OF 5-CHLORO-2-OXYINDOLE | KURARAY CO LTD | 1995-08-01 | — | — | JP | disclosed |
| CN-1008733-B | Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces | PFIZER (US) | 1990-07-11 | — | — | CN | disclosed |
| CN-1007428-B | PROCESS FOR MAKING 2-OXINDOLE-1-CARBOXAMIDES AND INTERMEDIATES THEREFOR | PFIZER (US) | 1990-04-04 | — | — | CN | disclosed |
| CN-1003855-B | Process for preparing 1, 3-disubstituted 2-oxindoles | 美国辉瑞有限公司 | 1989-04-12 | — | — | CN | disclosed |
| CN-85101795-A | With 1, the two 2-oxyindoles that replace of 3-prepare pain killer and antiphlogistic | — | 1987-04-08 | — | — | CN | disclosed |
| CN-85103527-A | Preparation N, the method for the disubstituted 2-hydroxyindole of 3--1-hydroxyalkyl cooh amide | — | 1987-01-28 | — | — | CN | disclosed |
| CN-85101029-A | The method of preparation-2-oxyindole-1-methane amide and intermediate product thereof | — | 1987-01-24 | — | — | CN | disclosed |
| CN-85101028-A | Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces | — | 1987-01-17 | — | — | CN | disclosed |
| US-4256640-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | SHIONOGI & CO., LTD. (JP) | 1981-03-17 | — | — | US | disclosed |