Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138338 | 1.00 | HPGDS (0.47) | HPGDSEGFRHTTLMNAMAP4K4 | |
| SCHEMBL11617161 | 0.95 | HPGDS (0.50) | HPGDSEGFRHTTLMNAPAK1 | |
| SCHEMBL767164 | 0.93 | HPGDS (0.42) | HPGDSEGFRHTTLMNAMAP4K4 | |
| SCHEMBL21138216 | 0.87 | MAPK8 (0.44) | HPGDSHTTLMNAPAK1TP53 | |
| SCHEMBL21138485 | 0.85 | CD38 (0.40) | HPGDSEGFRHTTMAP4K4CYP3A4 | |
| SCHEMBL21138491 | 0.84 | JAK2 (0.49) | HPGDSEGFRTP53JAK2JAK1 | |
| SCHEMBL21138337 | 0.84 | JAK2 (0.49) | HPGDSEGFRTP53JAK2JAK1 | |
| SCHEMBL21138209 | 0.83 | HPGDS (0.37) | HPGDSEGFRMAP4K4TP53JAK2 | |
| SCHEMBL21057420 | 0.83 | HPGDS (0.37) | HPGDSEGFRMAP4K4TP53JAK2 | |
| SCHEMBL21138334 | 0.81 | MAPK8 (0.40) | HPGDSEGFRHTTLMNAPAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |