Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138338 | 0.93 | HPGDS (0.47) | HPGDSHTTRAB9AGALR3MAP4K4 | |
| SCHEMBL30808262 | 0.93 | HPGDS (0.47) | HPGDSHTTRAB9AGALR3MAP4K4 | |
| SCHEMBL21138485 | 0.92 | CD38 (0.40) | HPGDSHTTRAB9AGALR3MAP4K4 | |
| SCHEMBL11617161 | 0.91 | HPGDS (0.50) | HPGDSHTTRAB9AMAPTLMNA | |
| SCHEMBL21138215 | 0.83 | BTK (0.49) | HPGDSRAB9AGALR3IRAK4MAPT | |
| SCHEMBL21823020 | 0.83 | RAB9A (0.40) | HTTRAB9AGALR3MAPTGAA | |
| SCHEMBL30808247 | 0.83 | RAB9A (0.40) | HTTRAB9AGALR3MAPTGAA | |
| SCHEMBL24286416 | 0.82 | RAB9A (0.39) | HTTRAB9AGALR3IRAK4MAPT | |
| SCHEMBL10475553 | 0.82 | RAB9A (0.39) | HTTRAB9AGALR3IRAK4MAPT | |
| SCHEMBL303845 | 0.81 | PAK1 (0.47) | RAB9APAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616469-B1 | 9H-PURINE COMPOUNDS AS PI3K-DELTA INHIBITORS AND METHODS FOR THEIR MANUFACTURE | EXELIXIS INC (US) | 2016-10-26 | — | — | EP | disclosed |
| US-9346807-B2 | Inhibitors of PI3K-delta and methods of their use and manufacture | EXELIXIS, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-9346807-B2 | Inhibitors of PI3K-delta and methods of their use and manufacture | EXELIXIS, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-9346807-B2 | Inhibitors of PI3K-delta and methods of their use and manufacture | EXELIXIS, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| EP-2398778-B1 | AMINOPYRIDINEAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-03-26 | — | — | EP | disclosed |
| EP-2398778-B1 | AMINOPYRIDINEAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-03-26 | — | — | EP | disclosed |
| US-20140058103-A1 | Inhibitors of PI3K-Delta and Methods of Their Use and Manufacture | EXELIXIS, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140058103-A1 | Inhibitors of PI3K-Delta and Methods of Their Use and Manufacture | EXELIXIS, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140058103-A1 | Inhibitors of PI3K-Delta and Methods of Their Use and Manufacture | EXELIXIS, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-8202877-B2 | Aminopyrimidinamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | US | disclosed |
| EP-2398778-A1 | AMINOPYRIMIDINAMIDES AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2011-12-28 | — | — | EP | disclosed |
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (US) | 2010-11-25 | — | — | US | disclosed |
| EP-2246335-A1 | Aminopyridineamides as pesticides | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | disclosed |
| EP-2246335-A1 | Aminopyridineamides as pesticides | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010094406-A1 | AMINOPYRIMIDINAMIDES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010094406-A1 | AMINOPYRIMIDINAMIDES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | DDT, NPEPPS, PTMS | HPGDS 3939/4885HTT 2989/4885RAB9A 980/4885 |
| US-20140058103-A1 | Inhibitors of PI3K-Delta and Methods of Their Use and Manufacture | PIK3CD, PIK3CA, PIK3R5 | HPGDS 659/4885HTT 3547/4885RAB9A 596/4885 |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | NPEPPS, DDT, DNPEP | HPGDS 3896/4885HTT 3532/4885RAB9A 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.