Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21821442 | 1.00 | PDE4B (0.55) | PDE4BPDE3APDE3BPDE4APDE4C | |
| SCHEMBL20529210 | 0.85 | PDE4B (0.55) | PDE4BPDE3APDE3BPDE4APDE4C | |
| SCHEMBL21821502 | 0.79 | PDE4B (0.51) | PDE4BPDE3APDE3BPDE4APDE4C | |
| SCHEMBL30808302 | 0.79 | PDE4B (0.51) | PDE4BPDE3APDE3BPDE4APDE4C | |
| SCHEMBL11568277 | 0.78 | HRH3 (0.50) | PDE4BPDE3APDE3BPDE4APDE4C | |
| SCHEMBL20159394 | 0.72 | HRH3 (0.50) | PDE4BPDE3APDE3BPDE4APDE4C | |
| SCHEMBL20138742 | 0.72 | HRH3 (0.53) | PDE4BPDE3APDE3BPDE4APDE4C | |
| SCHEMBL6405046 | 0.70 | PDE3B (0.44) | PDE4BPDE3APDE3BPDE4APDE4C | |
| SCHEMBL8714845 | 0.69 | HRH3 (0.44) | PDE4BPDE3APDE3BPDE4APDE4C | |
| SCHEMBL4302847 | 0.68 | DYRK1A (0.65) | PDE4ACHEK1DYRK1AKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |