Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1232197 | 1.00 | PGR (0.46) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL30809204 | 0.97 | PGR (0.46) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL30809082 | 0.93 | PGR (0.43) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL16324025 | 0.93 | PGR (0.43) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL17806128 | 0.87 | PGR (0.49) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL23671540 | 0.86 | MAPK14 (0.45) | PGRMAPK14 | |
| SCHEMBL13650414 | 0.81 | MAPK14 (0.42) | PGRMAPK14PDE4APDE4BPDE4C | |
| SCHEMBL13733446 | 0.75 | PGR (0.44) | PGRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1233666 | 0.75 | — | — | |
| SCHEMBL30809339 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543544-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023250064-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-12-28 | — | — | WO | disclosed |