⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233666 | 1.00 | — | — | |
| SCHEMBL13733446 | 0.79 | PGR (0.44) | — | |
| SCHEMBL16324025 | 0.77 | PGR (0.43) | — | |
| SCHEMBL30809082 | 0.77 | PGR (0.43) | — | |
| SCHEMBL1232197 | 0.75 | PGR (0.46) | — | |
| SCHEMBL30809074 | 0.75 | PGR (0.46) | — | |
| SCHEMBL30809204 | 0.75 | PGR (0.46) | — | |
| SCHEMBL30809228 | 0.72 | GSK3B (0.36) | — | |
| SCHEMBL23671540 | 0.71 | MAPK14 (0.45) | — | |
| SCHEMBL5485978 | 0.70 | CHRM2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543544-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119866338-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-22 | — | — | CN | disclosed |
| WO-2023250064-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-12-28 | — | — | WO | disclosed |