⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31691940 | 0.90 | — | — | |
| SCHEMBL31568031 | 0.83 | — | — | |
| SCHEMBL31691828 | 0.78 | TAS1R3 (0.30) | — | |
| SCHEMBL38654184 | 0.74 | TRPV1 (0.32) | — | |
| SCHEMBL31543585 | 0.73 | — | — | |
| SCHEMBL26685850 | 0.70 | WDR91 (0.31) | — | |
| SCHEMBL21812494 | 0.68 | CTH (0.35) | — | |
| SCHEMBL29187117 | 0.67 | KMT2A (0.30) | — | |
| SCHEMBL31543492 | 0.67 | — | — | |
| SCHEMBL26685227 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
| EP-4543544-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023250064-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-12-28 | — | — | WO | disclosed |