Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26915140 | 1.00 | HPGD (0.52) | HPGDKDM4ESMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL8053708 | 0.80 | KDM4E (0.57) | HPGDKDM4ESMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL26915241 | 0.79 | HPGD (0.48) | HPGDKDM4ESMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL31725099 | 0.79 | MAPK1 (0.47) | HPGDKDM4ESMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL26915214 | 0.79 | MAPK1 (0.47) | HPGDKDM4ESMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL30884749 | 0.78 | KDM4E (0.57) | HPGDKDM4ESMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL29084613 | 0.78 | KDM4E (0.57) | HPGDKDM4ESMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL21450559 | 0.78 | KDM4E (0.57) | HPGDKDM4ESMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL8961778 | 0.76 | KDM4E (0.55) | HPGDKDM4ESMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL21450560 | 0.75 | KDM4E (0.81) | HPGDKDM4ESMN1; SMN2NPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346606-A1 | CAMPTOTHECIN COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2025-11-13 | — | — | US | disclosed |
| CN-120058723-A | Camptothecins compound and its preparation method and application | 四川科伦博泰生物医药股份有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-117567478-B | Camptothecins compound and its preparation method and application | 四川科伦博泰生物医药股份有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-117567478-A | Camptothecins compound and its preparation method and application | 四川科伦博泰生物医药股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346606-A1 | CAMPTOTHECIN COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | WEE1, WEE2, PCLAF | HPGD 696/4885KDM4E 4289/4885SMN1; SMN2 4249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.