Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612141 | 1.00 | KDM4E (0.43) | KDM4EHPGDALDH1A1NPSR1ABL1 | |
| SCHEMBL30810287 | 0.87 | KDM4E (0.45) | KDM4EHPGDALDH1A1NPSR1ABL1 | |
| SCHEMBL30810313 | 0.86 | KDM4E (0.48) | KDM4EHPGDALDH1A1NPSR1ABL1 | |
| SCHEMBL19612138 | 0.86 | KDM4E (0.48) | KDM4EHPGDALDH1A1NPSR1ABL1 | |
| SCHEMBL30810366 | 0.86 | KDM4E (0.52) | KDM4EHPGDALDH1A1ACLYGAA | |
| SCHEMBL30810413 | 0.83 | KMT2A (0.43) | KDM4EHPGDALDH1A1NPSR1ABL1 | |
| SCHEMBL19612171 | 0.82 | ALDH1A1 (0.41) | KDM4EHPGDALDH1A1NPSR1ABL1 | |
| SCHEMBL30810291 | 0.82 | ABL1 (0.42) | KDM4EHPGDALDH1A1NPSR1ABL1 | |
| SCHEMBL19612155 | 0.82 | ABL1 (0.42) | KDM4EHPGDALDH1A1NPSR1ABL1 | |
| SCHEMBL30810216 | 0.81 | KDM4E (0.40) | KDM4EHPGDALDH1A1NPSR1GALK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583870-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | Mito Biopharma, LLC (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054766-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | MITO BIOPHARMA, LLC (US) | 2024-03-14 | — | — | WO | disclosed |