Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30239427 | 0.91 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10ACLY | |
| SCHEMBL18393285 | 0.84 | GALK1 (0.51) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL11179872 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL30810259 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL19612124 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL30084374 | 0.81 | ACLY (0.56) | KDM4EALDH1A1HPGDHSD17B10ACLY | |
| SCHEMBL423692 | 0.81 | ACLY (0.56) | KDM4EALDH1A1HPGDHSD17B10ACLY | |
| SCHEMBL10994738 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HPGDNPSR1ACLY | |
| SCHEMBL4129252 | 0.81 | HSD17B10 (0.49) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL13280732 | 0.81 | ABL1 (0.60) | KDM4EALDH1A1HPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583870-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | Mito Biopharma, LLC (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054766-A2 | MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER | MITO BIOPHARMA, LLC (US) | 2024-03-14 | — | — | WO | disclosed |