SCHEMBL308103

SCHEMBL308103

O=C1[CH]CCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL293677 0.82
SCHEMBL195173 0.80
SCHEMBL5161081 0.78
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL5086136 0.71
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL49488 0.71
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL31482438 0.69
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL9464948 0.69
SCHEMBL5163624 0.69
SCHEMBL3675360 0.67 GSK3A (0.47)
SCHEMBL3675358 0.67 GSK3A (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1700 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399209-A1 NEW QUINOLINE DERIVATIVES Elanco Animal Health GmbH (DE) 2024-07-17 EP claimed
US-12012409-B2 Bicyclic heterocycles as FGFR inhibitors INCYTE CORPORATION (US) 2024-06-18 US claimed
US-20240150396-A1 INHIBITORS OF CYSTEINE PROTEASES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-05-09 US claimed
CN-117957223-A Quinoline derivatives 礼蓝动物保健有限公司 2024-04-30 CN claimed
WO-2024003259-A1 TEAD INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-04 WO claimed
US-20230416205-A1 COMPOUNDS, COMPOSITIONS, AND METHODS TENVIE THERAPEUTICS, INC. 2023-12-28 US claimed
EP-4263548-A1 DIHYDROFUROPYRIDINE DERIVATIVES AS RHO- KINASE INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2023-10-25 EP claimed
EP-4247376-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Denali Therapeutics Inc. (US) 2023-09-27 EP claimed
EP-4216961-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CORONAVIRUS INFECTION Lighthouse Pharmaceuticals, Inc. (US) 2023-08-02 EP claimed
CN-116507608-A Compounds, compositions, and methods 戴纳立制药公司 2023-07-28 CN claimed
CN-1041944-A The preparation method of penem PFIZER (US) 1990-05-09 CN claimed
EP-0365223-A2 Process for the preparation of penems PFIZER INC. (US) 1990-04-25 EP claimed
US-4895940-A Process for the preparation of penems PFIZER INC. (US) 1990-01-23 US claimed
EP-0138539-B1 2-AZACYCLOALKYLTHIOPENEM DERIVATIVES PFIZER INC. (US) 1989-03-15 EP claimed
EP-0131374-B1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PENEM DERIVATIVES PFIZER INC. (US) 1988-11-23 EP claimed
US-4772597-A ANTIBIOTICS PFIZER INC. (US) 1988-09-20 US claimed
EP-0241901-A2 Cephalosporin derivatives, processes for their preparation and antibacterial agents Banyu Pharmaceutical Co., Ltd. (JP) 1987-10-21 EP claimed
US-4619783-A BACTERICIDES PFIZER INC. (US) 1986-10-28 US claimed
EP-0138539-A1 2-Azacycloalkylthiopenem derivatives PFIZER INC. (US) 1985-04-24 EP claimed
EP-0131374-A1 Process and intermediates for the preparation of penem derivatives PFIZER INC. (US) 1985-01-16 EP claimed