⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195173 | 0.92 | — | — | |
| SCHEMBL308103 | 0.82 | — | — | |
| SCHEMBL651905 | 0.74 | — | — | |
| SCHEMBL5163442 | 0.74 | — | — | |
| SCHEMBL541182 | 0.67 | — | — | |
| SCHEMBL541181 | 0.67 | — | — | |
| SCHEMBL4279648 | 0.67 | — | — | |
| SCHEMBL23610158 | 0.65 | — | — | |
| SCHEMBL4954677 | 0.65 | ALDH1A1 (0.39) | — | |
| SCHEMBL4954673 | 0.65 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 696 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138795-A1 | DOPAMINE-B-HYDROXYLASE INHIBITORS | BIAL PORTELA & CA SA (PT) | 2023-05-04 | — | — | US | claimed |
| CN-114181198-A | Pyrimidine derivative ketohexokinase inhibitor and application thereof | 山东轩竹医药科技有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-107849044-B | Triaza-spirodecanones as DDR1 inhibitors | 豪夫迈·罗氏有限公司 | 2021-06-25 | — | — | CN | claimed |
| US-20210171528-A1 | DOPAMINE-B-HYDROXYLASE INHIBITORS | BIAL - PORTELA & CA, S.A. (PT) | 2021-06-10 | — | — | US | claimed |
| CN-112638917-A | Heterocyclic compounds as kinase inhibitors, compositions comprising the heterocyclic compounds, and methods of use thereof | 捷思英达控股有限公司 | 2021-04-09 | — | — | CN | claimed |
| EP-3797109-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS COMPRISING THE HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF | JS Innomed Holdings Ltd. (KY) | 2021-03-31 | — | — | EP | claimed |
| EP-3317279-B1 | TRIAZA-SPIRODECANONES AS DDR1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2021-01-27 | — | — | EP | claimed |
| EP-3720856-A1 | DOPAMINE-& X392;-HYDROXYLASE INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2020-10-14 | — | — | EP | claimed |
| CN-111479812-A | dopamine-B-hydroxylase inhibitors | 巴尔-波特拉及康邦亚股份有限公司 | 2020-07-31 | — | — | CN | claimed |
| US-10590083-B2 | Pyridin-2-one derivatives of formula (I) useful as EP3 receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2020-03-17 | — | — | US | claimed |
| US-6743788-B2 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASE; AUTOIMMUNE DISEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-06-01 | — | — | US | claimed |
| EP-1395561-A1 | CARBAMATE AND OXAMIDE COMPOUNDS AS INHIBITORS OF CYTOKINE PRODUCTION | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-03-10 | — | — | EP | claimed |
| US-20030092702-A1 | Novel carbamate and oxamide compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | US | claimed |
| WO-2002096876-A1 | CARBAMATE AND OXAMIDE COMPOUNDS AS INHIBITORS OF CYTOKINE PRODUCTION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | claimed |
| EP-0138539-B1 | 2-AZACYCLOALKYLTHIOPENEM DERIVATIVES | PFIZER INC. (US) | 1989-03-15 | — | — | EP | claimed |
| EP-0131374-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PENEM DERIVATIVES | PFIZER INC. (US) | 1988-11-23 | — | — | EP | claimed |
| US-4772597-A | ANTIBIOTICS | PFIZER INC. (US) | 1988-09-20 | — | — | US | claimed |
| US-4619783-A | BACTERICIDES | PFIZER INC. (US) | 1986-10-28 | — | — | US | claimed |
| EP-0138539-A1 | 2-Azacycloalkylthiopenem derivatives | PFIZER INC. (US) | 1985-04-24 | — | — | EP | claimed |
| EP-0131374-A1 | Process and intermediates for the preparation of penem derivatives | PFIZER INC. (US) | 1985-01-16 | — | — | EP | claimed |