5,6-Dihydro-2(1H)-Pyridinone

5,6-Dihydro-2(1H)-Pyridinone

SCHEMBL5086136

O=C1[CH][CH]CCN1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL308103 0.71
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL49488 0.67
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL9464948 0.65
5,6-Dihydro-2(1H)-Pyridinone SCHEMBL31482438 0.65
SCHEMBL3675358 0.63 GSK3A (0.47)
SCHEMBL3675360 0.63 GSK3A (0.47)
SCHEMBL5163707 0.63
SCHEMBL293677 0.61
SCHEMBL195173 0.59
SCHEMBL30922191 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1991215-A1 USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES Cenix Bioscience GmbH (DE) 2008-11-19 EP disclosed
WO-2007101710-A1 USE OF INHIBITORS OF SCAVENGER RECEPTOR CLASS PROTEINS FOR THE TREATMENT OF INFECTIOUS DISEASES CENIX BIOSCIENCE GMBH (DE) 2007-09-13 WO disclosed