Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 11/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | SNCA | P37840 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174399 | 1.00 | NOX1 (0.59) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL4625689 | 1.00 | NOX1 (0.59) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL11280393 | 0.91 | SNCA (0.46) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL11272621 | 0.90 | NOX1 (0.59) | NOX1MAPTGAASNCAMEN1 | |
| Phenothiazine SCHEMBL28891489 | 0.84 | NOX1 (0.65) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL11391722 | 0.83 | L3MBTL1 (0.64) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL8722738 | 0.83 | NOX1 (0.59) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL11277664 | 0.80 | NOX1 (0.43) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL31512613 | 0.79 | NOX1 (0.53) | NOX1MAPTGAASNCAMEN1 | |
| Phenothiazine SCHEMBL28091707 | 0.77 | NOX1 (0.74) | NOX1MAPTGAASNCAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543863-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | University Of Ottawa (CA) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |