Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 11/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | SNCA | P37840 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174399 | 1.00 | NOX1 (0.59) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL30811560 | 1.00 | NOX1 (0.59) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL11280393 | 0.91 | SNCA (0.46) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL11272621 | 0.90 | NOX1 (0.59) | NOX1MAPTGAASNCAMEN1 | |
| Phenothiazine SCHEMBL28891489 | 0.84 | NOX1 (0.65) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL11391722 | 0.83 | L3MBTL1 (0.64) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL8722738 | 0.83 | NOX1 (0.59) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL11277664 | 0.80 | NOX1 (0.43) | NOX1MAPTGAASNCAMEN1 | |
| SCHEMBL31512613 | 0.79 | NOX1 (0.53) | NOX1MAPTGAASNCAMEN1 | |
| Phenothiazine SCHEMBL28091707 | 0.77 | NOX1 (0.74) | NOX1MAPTGAASNCAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506159-A | Compounds having CRTH2 antagonist activity | OXAGEN LTD (GB) | 2009-08-12 | — | — | CN | claimed |
| CN-1662529-A | Thiazole derivatives as phosphodiesterase IV inhibitors | MERCK PATENT GMBH (DE) | 2005-08-31 | — | — | CN | claimed |
| CN-1659148-A | Aryloximes | MERCK PATENT GMBH (DE) | 2005-08-24 | — | — | CN | claimed |
| CN-1659147-A | Pyridazine derivatives | MERCK PATENT GMBH (DE) | 2005-08-24 | — | — | CN | claimed |
| CN-1608067-A | Pyrrolopyrimidines as phosphodiesterase vii inhibitors | MERCK PATENT GMBH (DE) | 2005-04-20 | — | — | CN | claimed |
| CN-1585641-A | Hydrazono-malonitriles | MERCK PATENT GMBH (DE) | 2005-02-23 | — | — | CN | claimed |
| CN-1578665-A | Type 4 phosphodiesterase inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2005-02-09 | — | — | CN | claimed |
| CN-1527830-A | Ether derivatives useful as inhibitors of PDE4 isozymes | �Ʒ� | 2004-09-08 | — | — | CN | claimed |
| CN-1518542-A | Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes | �Ʒ� | 2004-08-04 | — | — | CN | claimed |
| CN-1489588-A | Thiazolyl-oxazolyl-pyrrolyl-and imidazolyl-acid amide derivatives useful as inbibitors of PDE 4 isozymes | �Ʒ� | 2004-04-14 | — | — | CN | claimed |
| CN-1483026-A | Benzoylpyridazines | Ĭ��ר���ɷ�����˾ | 2004-03-17 | — | — | CN | claimed |
| CN-1404481-A | Nicotinamide benzofused heterocyclic derivatives useful as selective inhibitors of PDE4 isozymes | PFIZER PROD INC (US) | 2003-03-19 | — | — | CN | claimed |
| CN-1404480-A | Pyrimidine carboxamides as inhibitors of the PDE4 isozyme | PFIZER PROD INC (US) | 2003-03-19 | — | — | CN | claimed |
| US-20260109678-A1 | SUBSTITUTED PHENOTHIAZINES AS FERROPTOSIS INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2026-04-23 | — | — | US | disclosed |
| US-20250326726-A1 | FERROPTOSIS INHIBITORS-PHENOXAZINE ACETAMIDES | SIRONAX BEIJING CO LTD (CN) | 2025-10-23 | — | — | US | disclosed |
| CN-119866332-A | Iron death inhibitor-phenoxazine acetamides | 维泰瑞隆（北京）生物科技有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-1284075-A | Novel compounds having CGMP-PDE inhibitory effect | MOCHIDA PHARM CO LTD (JP) | 2001-02-14 | — | — | CN | disclosed |
| WO-2000017191-A2 | N-(IMINOMETHYL)AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-03-30 | — | — | WO | disclosed |
| US-5756356-A | COLORIMETRIC | TOYO INK MANUFACTURING CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0735368-A1 | Method of indicating time or temperature-time accumulated value as color change, and materials therefor | TOYO INK MANUFACTURING CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326726-A1 | FERROPTOSIS INHIBITORS-PHENOXAZINE ACETAMIDES | AIFM2, GPX4, FECH | NOX1 1192/4885MAPT 3646/4885GAA 4048/4885 |
| US-20260109678-A1 | SUBSTITUTED PHENOTHIAZINES AS FERROPTOSIS INHIBITORS | AIFM2, HMOX1, ARG2 | NOX1 105/4885MAPT 1357/4885GAA 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.