Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30811690 | 0.98 | KDM4E (0.68) | KDM4EMEN1ALDH1A1KMT2AMKNK1 | |
| SCHEMBL30811844 | 0.82 | ALDH1A1 (1.00) | KDM4EMEN1ALDH1A1KMT2AMKNK1 | |
| SCHEMBL2841794 | 0.79 | SIRT2 (0.54) | KDM4EMEN1ALDH1A1KMT2AMKNK1 | |
| SCHEMBL3509627 | 0.78 | ALDH1A1 (0.66) | KDM4EMEN1ALDH1A1KMT2ACYP11B1 | |
| SCHEMBL28505725 | 0.77 | ALDH1A1 (0.64) | KDM4EMEN1ALDH1A1KMT2AHDAC1 | |
| SCHEMBL28333029 | 0.74 | CYP2C19 (0.64) | KDM4EMEN1ALDH1A1KMT2ASIRT2 | |
| SCHEMBL832732 | 0.74 | HCAR2 (0.67) | KDM4EMEN1ALDH1A1KMT2AMKNK1 | |
| SCHEMBL4477190 | 0.74 | MKNK1 (0.66) | KDM4EMEN1ALDH1A1KMT2AMKNK1 | |
| SCHEMBL29503159 | 0.74 | HCAR2 (0.67) | KDM4EMEN1ALDH1A1KMT2AMKNK1 | |
| SCHEMBL9607829 | 0.73 | SMYD3 (0.52) | KDM4EMKNK1MKNK2RAF1PKMYT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024056099-A1 | METTL3 INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 北京华益健康药物研究中心 | 2024-03-21 | — | — | WO | disclosed |
| CN-117720533-A | MetTL3 inhibitor compound and pharmaceutical composition and application thereof | 北京华益健康药物研究中心 | 2024-03-19 | — | — | CN | disclosed |