Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.57 |
| ▸ | TOP2A | P11388 | 6/20 | 0.56 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10790810 | 0.91 | TOP2A (0.61) | KCNH2TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL30811883 | 0.90 | KCNH2 (0.55) | KCNH2TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL9668066 | 0.90 | TOP2A (0.62) | KCNH2TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL10785816 | 0.90 | TOP2A (0.62) | KCNH2TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL30811877 | 0.89 | ALDH1A1 (0.70) | KCNH2TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL30811874 | 0.89 | TOP2A (0.52) | KCNH2TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL10736927 | 0.85 | TOP2A (0.60) | KCNH2TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL7821381 | 0.85 | KDM4E (0.69) | KCNH2TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL8323350 | 0.85 | ALDH1A1 (0.59) | KCNH2TOP2ATOP2BALDH1A1POLB | |
| SCHEMBL8616936 | 0.85 | ALDH1A1 (0.66) | KCNH2TOP2ATOP2BALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903163-A | Fluoroquinolone compound with spiro structure at C7 position and application thereof | 广东工业大学 | 2024-04-19 | — | — | CN | disclosed |