SCHEMBL30811997

SCHEMBL30811997

Cn1cc(-c2cc(C(C)(C)O)ccc2OC(CCCCCN2CCNCC2)C2CC2)c2cc[nH]c2c1=O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ BRD9 Q9H8M2 3/20 0.45
▸ BRD4 O60885 17/20 0.43
▸ HDAC1 Q13547 2/20 0.43
▸ HDAC6 Q9UBN7 2/20 0.43
▸ HDAC3 O15379 1/20 0.43
▸ HDAC8 Q9BY41 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30812160 0.85 BRD4 (0.46) BRD9BRD4
SCHEMBL27393085 0.85 BRD4 (0.59) BRD4
SCHEMBL30812077 0.85 BRD4 (0.62) BRD4
SCHEMBL30812019 0.81 BRD4 (0.41) BRD4HDAC1HDAC6HDAC3HDAC8
SCHEMBL30812291 0.78 ALDH1A1 (0.36) —
SCHEMBL31245971 0.77 BRD4 (0.48) BRD9BRD4
SCHEMBL27393082 0.77 BRD4 (0.62) BRD4
SCHEMBL30812064 0.77 BRD4 (0.71) BRD4
SCHEMBL30812230 0.76 BRD4 (0.51) BRD4
SCHEMBL30812225 0.75 BRD4 (0.52) BRD9BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388605-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO INC (US) 2025-12-25 — — US disclosed
WO-2024054956-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2024-03-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388605-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE BRD4, BRDT, BICRA BRD9 10/4885BRD4 1/4885HDAC1 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback