Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30812271 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EHTTLMNAMEN1 | |
| SCHEMBL30811997 | 0.78 | BRD9 (0.45) | — | |
| SCHEMBL31246021 | 0.69 | UTS2R (0.35) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL31246003 | 0.67 | KDM4E (0.48) | ALDH1A1KDM4EHTTLMNAMEN1 | |
| SCHEMBL24083945 | 0.63 | KMT2A (0.56) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL30812175 | 0.63 | UTS2R (0.35) | UTS2RHTR1ACYP2D6DRD2HTR2C | |
| SCHEMBL24083883 | 0.63 | MEN1 (0.59) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL11496309 | 0.63 | ALDH1A1 (0.43) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL31063294 | 0.63 | PDE4A (0.43) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL24377888 | 0.62 | KMT2A (0.55) | ALDH1A1KDM4EHTTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054956-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |