Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30812085 | 0.85 | PKM (0.40) | GPR119ABCB1 | |
| SCHEMBL30812071 | 0.85 | BRD4 (0.43) | BRD4GPR119MMP13 | |
| SCHEMBL30811971 | 0.81 | BRD4 (0.70) | BRD4 | |
| SCHEMBL30812078 | 0.79 | POLB (0.34) | — | |
| SCHEMBL30812273 | 0.78 | BRD4 (0.49) | BRD4 | |
| SCHEMBL27393072 | 0.77 | GPR119 (0.47) | GPR119 | |
| SCHEMBL30824813 | 0.77 | GPR119 (0.47) | GPR119 | |
| SCHEMBL15068074 | 0.75 | BRD4 (0.59) | BRD4GPR119 | |
| SCHEMBL30824886 | 0.73 | RXFP1 (0.44) | BRD4GPR119 | |
| SCHEMBL27390617 | 0.73 | RXFP1 (0.44) | BRD4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054956-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |