SCHEMBL3081241

SCHEMBL3081241

CCCCCCOc1ccccc1OCC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 7/20 0.67
MAPT P10636 4/20 0.58
NPSR1 Q6W5P4 1/20 0.58
ALDH1A1 P00352 3/20 0.57
MEN1 O00255 2/20 0.57
LMNA P02545 2/20 0.57
KMT2A Q03164 2/20 0.57
NR1I2 O75469 1/20 0.57
CHRM2 P08172 1/20 0.57
CYP3A4 P08684 1/20 0.57
ADRA2A P08913 1/20 0.57
OPRK1 P41145 1/20 0.57
HTR2B P41595 1/20 0.57
SLC6A3 Q01959 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
CYP1A2 P05177 2/20 0.55
CYP2C19 P33261 2/20 0.55
CYP2C9 P11712 1/20 0.55
TDP1 Q9NUW8 2/20 0.55
CYP2D6 P10635 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7639583 1.00 L3MBTL1 (0.67) L3MBTL1MAPTNPSR1ALDH1A1MEN1
SCHEMBL7636542 1.00 L3MBTL1 (0.67) L3MBTL1MAPTNPSR1ALDH1A1MEN1
SCHEMBL28515930 1.00 L3MBTL1 (0.67) L3MBTL1MAPTNPSR1ALDH1A1MEN1
1-Ethoxy-2-Pentoxybenzene SCHEMBL1276813 0.98 L3MBTL1 (0.69) L3MBTL1MAPTNPSR1ALDH1A1MEN1
SCHEMBL2859001 0.94 LMNA (0.62) L3MBTL1MAPTALDH1A1MEN1LMNA
SCHEMBL1778134 0.94 LMNA (0.62) L3MBTL1MAPTALDH1A1MEN1LMNA
SCHEMBL9387360 0.94 LMNA (0.62) L3MBTL1MAPTALDH1A1MEN1LMNA
SCHEMBL2245919 0.94 LMNA (0.62) L3MBTL1MAPTALDH1A1MEN1LMNA
SCHEMBL9394792 0.94 LMNA (0.62) L3MBTL1MAPTALDH1A1MEN1LMNA
SCHEMBL1276613 0.94 L3MBTL1 (0.74) L3MBTL1MAPTNPSR1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399837-B1 POLYMERIZATION CATALYST FOR OLEFINS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2002-06-04 US claimed
EP-0926119-A1 Dialkoxybenzene electron donors UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-06-30 EP claimed
US-20100273641-A1 Self-Limiting Catalyst Composition with Non-Phthalate Internal Donor W. R. GRACE & CO.-CONN. 2010-10-28 US disclosed
EP-0922712-B1 Novel electron donor containing compositions UNION CARBIDE CHEM PLASTIC (US) 2002-12-18 EP disclosed
US-6399837-B1 POLYMERIZATION CATALYST FOR OLEFINS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2002-06-04 US disclosed
US-6124507-A USED IN THE MANUFACTURE OF OLEFIN POLYMERIZATION CATALYSTS WITH PROCATALYSTS HAVING MAGNESIUM, TITANIUM AND HALIDE AS ESSENTIAL COMPONENTS. 1-ETHOXY-2-ALKOXY-4,5,6-OPTIONALLY SUBSTITUTED BENZENES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-09-26 US disclosed
US-5968865-A COORDINATION CATALYST COMPRISING MAGNESIUM, TITANIUM, HALIDE, AND 1,2-DIALKOXYBENZENE COMPOUNDS; OLEFIN POLYMERIZATION CATALYSTS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-10-19 US disclosed
EP-0926119-A1 Dialkoxybenzene electron donors UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-06-30 EP disclosed
EP-0922712-A1 Novel electron donor containing compositions UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-06-16 EP disclosed