Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30813079 | 0.91 | PREP (0.49) | PREPDHODH | |
| SCHEMBL30813042 | 0.87 | MAOB (0.40) | PREP | |
| SCHEMBL30813059 | 0.87 | ALDH1A1 (0.49) | PREP | |
| SCHEMBL30813161 | 0.85 | MAOB (0.48) | PREP | |
| SCHEMBL30813116 | 0.83 | MAOB (0.46) | — | |
| SCHEMBL30813082 | 0.83 | HCRTR1 (0.44) | — | |
| SCHEMBL30813182 | 0.82 | PTGDR2 (0.42) | PREPDHODH | |
| SCHEMBL30813076 | 0.81 | ALDH1A1 (0.52) | DHODH | |
| SCHEMBL30813053 | 0.81 | LMNA (0.45) | DHODH | |
| SCHEMBL30813172 | 0.80 | KMT2A (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3455224-B1 | SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF | BAYER AG (DE) | 2024-03-27 | — | — | EP | disclosed |