Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30813120 | 0.84 | MEN1 (0.38) | PREPMEN1KMT2AHTR2CHTR2B | |
| SCHEMBL30813076 | 0.84 | ALDH1A1 (0.52) | MEN1KMT2A | |
| SCHEMBL30813226 | 0.82 | PREP (0.45) | PREP | |
| SCHEMBL30813223 | 0.82 | PREP (0.33) | PREP | |
| SCHEMBL30813155 | 0.80 | KDM4E (0.50) | MEN1KMT2A | |
| SCHEMBL30813103 | 0.80 | PREP (0.36) | PREP | |
| SCHEMBL30813132 | 0.79 | LMNA (0.35) | PREP | |
| SCHEMBL30813074 | 0.79 | NPSR1 (0.41) | KMT2A | |
| SCHEMBL30813161 | 0.78 | MAOB (0.48) | PREP | |
| SCHEMBL30813057 | 0.78 | PREP (0.48) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3455224-B1 | SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF | BAYER AG (DE) | 2024-03-27 | — | — | EP | disclosed |