SCHEMBL308136

SCHEMBL308136

O=C1N=C2N=CN=C2C(=O)N1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MPO P05164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634546 0.80 MPO (0.41) MPO
SCHEMBL4774365 0.80 MPO (0.34) MPO
SCHEMBL7617970 0.80 MPO (0.41) MPO
SCHEMBL563036 0.76 MPO (0.32) MPO
SCHEMBL9391191 0.75 MPO (0.33) MPO
SCHEMBL11755943 0.73
SCHEMBL4084535 0.71
SCHEMBL3305612 0.67
SCHEMBL1720840 0.65
SCHEMBL11133036 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 608 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110964013-B Preparation method of linagliptin and intermediate thereof 甘李药业股份有限公司 2023-04-07 CN claimed
WO-2023284087-A1 CLEANING COMPOSITION USED DURING CLEANING OF SEMICONDUCTOR WAFER AFTER CHEMICAL-MECHANICAL POLISHING 张家港安储科技有限公司 2023-01-19 WO claimed
CN-110964013-A Preparation method of linagliptin and intermediate thereof 甘李药业江苏有限公司 2020-04-07 CN claimed
WO-2015107533-A1 A PROCESS FOR PREPARATION OF 1H-PURINE-2,6-DIONE, 8-[(3R)-3-AMINO-1-PIPERIDINYL]-7 (2-BUTYN-1-YL)-3,7-DIHYDRO-3-METHYL-1-[(4-METHYL-2QUINAZOLINYL) METHYL] AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS HARMAN FINOCHEM LIMITED (IN) 2015-07-23 WO claimed
EP-2268641-A2 HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST Advinus Therapeutics Pvt. Ltd. (IN) 2011-01-05 EP claimed
EP-2146996-A1 XANTHINE COMPOUNDS HAVING A POSITIVE ALLOSTERIC GABAB RECEPTOR MODULATOR EFFECT AstraZeneca AB (SE) 2010-01-27 EP claimed
EP-2111231-A2 METHODS AND COMPOSITIONS FOR IMPROVING IMMUNE RESPONSES NorthEastern University (US) 2009-10-28 EP claimed
WO-2009118759-A2 HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST ADVINUS THERAPEUTICS PVT. LTD., (IN) 2009-10-01 WO claimed
WO-2008147482-A2 METHODS AND COMPOSITIONS FOR IMPROVING IMMUNE RESPONSES NORTHEASTERN UNIVERSITY (US) 2008-12-04 WO claimed
WO-2008130314-A1 XANTHINE COMPOUNDS HAVING A POSITIVE ALLOSTERIC GABAB RECEPTOR MODULATOR EFFECT ASTRAZENECA AB (SE) 2008-10-30 WO claimed
US-5359080-A Acetylacetamide couplers; high sensitivity, color density, spectral absorption FUJI PHOTO FILM CO., LTD. (JP) 1994-10-25 US claimed
US-5294524-A Acylacetamide yellow dye-forming couplers and aromatic amine developers FUJI PHOTO FILM CO., LTD. (JP) 1994-03-15 US claimed
EP-0151826-B1 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines JANSSEN PHARMACEUTICA N.V. (BE) 1993-03-31 EP claimed
WO-1992007852-A1 BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS G.D. SEARLE & CO. (US) 1992-05-14 WO claimed
CN-1057911-A Form the coupling agent of weld and the color silver halide photographic-material that contains this coupling agent FUJI PHOTO FILM CO LTD (JP) 1992-01-15 CN claimed
EP-0447969-A1 Yellow dye-forming coupler and silver halide color photographic material containing same FUJI PHOTO FILM CO., LTD. (JP) 1991-09-25 EP claimed
EP-0252043-A1 Method for the preparation of 3-n-propyl-xanthine Aktiebolaget Draco (SE) 1988-01-07 EP claimed
US-4670438-A Imidazo[4,5-c]pyridazine-3-ones, imidazo[4,5-d]pyridazine-4-ones, imidazo[4,]pyrazin-5-ones, purin-2-ones, purin-6-ones, and purin-2,6-diones useful as hypotensive or cardiotonic agents DR. KARL THOMAE GMBH (DE) 1987-06-02 US claimed
EP-0184738-A2 Imidazole derivatives, medicaments containing these compounds, and process for their preparation Dr. Karl Thomae GmbH (DE) 1986-06-18 EP claimed
EP-0130461-A2 Imidazoles, their preparation, and medicaments containing these compounds Dr. Karl Thomae GmbH (DE) 1985-01-09 EP claimed