Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308136 | 0.80 | MPO (0.36) | MPO | |
| SCHEMBL3801963 | 0.80 | MPO (0.36) | MPO | |
| SCHEMBL4774365 | 0.77 | MPO (0.34) | MPO | |
| SCHEMBL7617970 | 0.73 | MPO (0.41) | MPO | |
| SCHEMBL563036 | 0.73 | MPO (0.32) | MPO | |
| SCHEMBL7624091 | 0.65 | — | — | |
| SCHEMBL3305612 | 0.64 | — | — | |
| SCHEMBL1720840 | 0.63 | — | — | |
| SCHEMBL8847459 | 0.61 | — | — | |
| SCHEMBL2523527 | 0.60 | DHFR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126439-A | Complementary purines and pyrimidines | TEMPLE UNIVERSITY (US) | 1992-06-30 | — | — | US | claimed |
| US-5126439-A | Complementary purines and pyrimidines | TEMPLE UNIVERSITY (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0333832-B1 | ARTIFICIAL DNA BASE PAIR ANALOGUES | TEMPLE UNIVERSITY (US) | 1992-06-03 | — | — | EP | disclosed |
| EP-0333832-A1 | ARTIFICIAL DNA BASE PAIR ANALOGUES | TEMPLE UNIVERSITY (US) | 1989-09-27 | — | — | EP | disclosed |
| WO-1989002921-A1 | ARTIFICIAL DNA BASE PAIR ANALOGUES | TEMPLE UNIVERSITY (US) | 1989-04-06 | — | — | WO | disclosed |