Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103711 | 0.88 | MAPT (0.35) | CYP1A2HPGDMAPK1CYP2C9HIF1A | |
| SCHEMBL20977392 | 0.85 | — | — | |
| Diethylaminoethanol SCHEMBL10476578 | 0.84 | CYP1A2 (0.42) | CYP1A2HPGDMAPK1CYP2C9HIF1A | |
| Deanol SCHEMBL2059818 | 0.84 | CYP1A2 (0.47) | CYP1A2HPGDMAPK1CYP2C9HIF1A | |
| SCHEMBL14504379 | 0.81 | CYP1A2 (0.43) | CYP1A2HPGDMAPK1CYP2C9HIF1A | |
| SCHEMBL367364 | 0.80 | PAX8 (0.31) | — | |
| SCHEMBL25372183 | 0.79 | CYP1A2 (0.42) | CYP1A2HPGDMAPK1CYP2C9HIF1A | |
| Hydrochloric Acid SCHEMBL8589282 | 0.78 | — | — | |
| Trolamine SCHEMBL4518758 | 0.75 | MAPT (0.36) | CYP1A2HPGDMAPK1CYP2C9HIF1A | |
| Diethylaminoethanol SCHEMBL16774691 | 0.75 | CYP1A2 (0.50) | CYP1A2HPGDMAPK1CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024046221-A1 | EGFR INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2024-03-07 | — | — | WO | disclosed |