Trolamine

Trolamine

SCHEMBL4518758

CC(C)(N)CO.OCCN(CCO)CCO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.36
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
MAPK1 P28482 2/20 0.35
KDM4E B2RXH2 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HTT P42858 1/20 0.35
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31
BCHE P06276 1/20 0.31
TSHR P16473 2/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL11034528 0.91 MAPT (0.55) MAPTALDH1A1HPGDMAPK1KDM4E
Trolamine SCHEMBL11034525 0.89 KDM4E (0.31) MAPTALDH1A1HPGDMAPK1KDM4E
Deanol SCHEMBL2059818 0.87 CYP1A2 (0.47) MAPTALDH1A1HPGDMAPK1KDM4E
Diethylaminoethanol SCHEMBL10476578 0.87 CYP1A2 (0.42) MAPTALDH1A1HPGDMAPK1KDM4E
Trolamine SCHEMBL11034532 0.85 MAPT (0.32) MAPT
SCHEMBL5965815 0.84 ARG1 (0.36) MAPTALDH1A1HPGDMAPK1KDM4E
SCHEMBL5014917 0.84 ARG1 (0.36) MAPTALDH1A1HPGDMAPK1KDM4E
Trolamine SCHEMBL28164611 0.83 MAPT (0.36) MAPTALDH1A1HPGDMAPK1KDM4E
Deanol SCHEMBL7163532 0.81 MAPT (0.63) MAPTALDH1A1MEN1LMNAKMT2A
Deanol SCHEMBL11550979 0.81 DRD2 (0.32) KDM4EMEN1LMNAKMT2AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107383313-A A kind of filled-type rigid composite material based on vamp leftover pieces and preparation method thereof 河北科技大学 2017-11-24 CN claimed
US-8668955-B2 Single step milling and surface coating process for preparing stable nanodispersions NANOMATERIALES S.A. DE C.V. (MX) 2014-03-11 US claimed
US-20130121936-A1 Single Step Milling and Surface Coating Process for Preparing Stable Nanodispersions NANOMATERIALES S.A. DE C.V. (MX) 2013-05-16 US claimed
US-8357426-B2 Single step milling and surface coating process for preparing stable nanodispersions NANOMATERIALES S.A. DE C.V. (MX) 2013-01-22 US claimed
US-20090180976-A1 SINGLE STEP MILLING AND SURFACE COATING PROCESS FOR PREPARING STABLE NANODISPERSIONS NANOBIOMAGNETICS, INC. 2009-07-16 US claimed
US-5077348-A Copolymer of acrylates, acrylated polyether, unsaturated acids and vinyl monomers blended with aqueous amine formaldehyde condensate TOYO INK MANUFACTURING CO., LTD. (JP) 1991-12-31 US claimed
CN-107383313-A A kind of filled-type rigid composite material based on vamp leftover pieces and preparation method thereof 河北科技大学 2017-11-24 CN disclosed
US-9260546-B2 Producing aqueous solutions of vinyllactam polymers and powders thereof BASF SE (DE) 2016-02-16 US disclosed
US-20140044662-A1 Producing Aqueous Solutions of Vinyllactam Polymers and Powders Thereof BASF SE (DE) 2014-02-13 US disclosed
EP-0634696-B2 Chemically amplified resist composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 2001-01-31 EP disclosed
US-6146704-A APPLYING AQUEOUS POLYMER DISPERSIONS BASED ON COPOLYMERS OF C2-C14 OLEFINS AND MONOMERS WHICH CONTAIN ACIDIC FUNCTIONAL GROUPS OR ARE ABLE TO FORM THEM BY HYDROLYSIS, WHICH DISPERSIONS MAY CONTAIN COLORANTS AND/OR CORROSION INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 2000-11-14 US disclosed
CN-1026569-C Special smooth-skin polyurethane foam plastic for oil seal TIANJIN POLYURETHANE PLASTICS (CN) 1994-11-16 CN disclosed