Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10174520 | 0.96 | KDM4E (0.43) | KDM4EGAAHSD17B10CASP1CASP7 | |
| SCHEMBL1224633 | 0.91 | KDM4E (0.43) | KDM4EGAAHSD17B10CASP1CASP7 | |
| SCHEMBL13527350 | 0.88 | ALDH1A1 (0.42) | KDM4EGAAHSD17B10CASP1CASP7 | |
| SCHEMBL18568164 | 0.88 | KDM4E (0.41) | KDM4EGAAHSD17B10CASP1CASP7 | |
| SCHEMBL13070829 | 0.88 | ALDH1A1 (0.43) | KDM4EGAAHSD17B10CASP1CASP7 | |
| SCHEMBL3001748 | 0.88 | KDM4E (0.41) | KDM4EGAAHSD17B10CASP1CASP7 | |
| SCHEMBL14400612 | 0.86 | HSP90AB1 (0.40) | KDM4EGAAHSD17B10CASP1CASP7 | |
| SCHEMBL2167805 | 0.85 | KMT2A (0.44) | KDM4EGAAHSD17B10CASP1CASP7 | |
| SCHEMBL1475954 | 0.83 | HSP90AB1 (0.43) | KDM4EGAAHSD17B10CASP1CASP7 | |
| SCHEMBL2428979 | 0.83 | KDM4E (0.38) | KDM4EGAAHSD17B10CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239468-A | Preparation method of 2- (2, 6-diethyl-4-methylphenyl) -malonic acid dimethyl ester | 上海工程技术大学 | 2023-06-09 | — | — | CN | claimed |
| CN-116239468-A | Preparation method of 2- (2, 6-diethyl-4-methylphenyl) -malonic acid dimethyl ester | 上海工程技术大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-116239468-A | Preparation method of 2- (2, 6-diethyl-4-methylphenyl) -malonic acid dimethyl ester | 上海工程技术大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-113121341-A | Method for synthesizing 2, 6-diethyl-4-methyl phenylacetate | 江苏中旗科技股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
| US-9758502-B2 | Dihydropyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-09-12 | — | — | US | disclosed |
| EP-2334175-B1 | PHENYL-SUBSTITUTED BICYCLOOCTANE 1,3 DIONE DERIVATIVES | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-2925736-B1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20150299156-A1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-10-22 | — | — | US | disclosed |
| US-8383853-B2 | Method for preparing 2,6-diethyl-4-methylphenylacetic acid | BAYER CROPSCIENCE AG (DE) | 2013-02-26 | — | — | US | disclosed |
| US-8367873-B2 | Phenyl-substituted bicyclooctane-1,3-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-05 | — | — | US | disclosed |
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20100261934-A1 | Method for Preparing 2,6-Diethyl-4-Methylphenylacetic Acid | BAYER CROPSCIENCE AG (DE) | 2010-10-14 | — | — | US | disclosed |
| US-20080318776-A1 | 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-12-25 | — | — | US | disclosed |
| CN-101094855-A | 2, 6-diethyl-4-methylphenyl substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2007-12-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | DDT, PIP5K1B, PIP5K1C | KDM4E 1388/4885GAA 527/4885HSD17B10 2508/4885 |
| US-20150299156-A1 | DIHYDROPYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | CBR3, DDT, WEE2 | KDM4E 699/4885GAA 3016/4885HSD17B10 147/4885 |
| US-20100261934-A1 | Method for Preparing 2,6-Diethyl-4-Methylphenylacetic Acid | DDT, TET1, DDC | KDM4E 303/4885GAA 342/4885HSD17B10 2174/4885 |
| US-20080318776-A1 | 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives | DDT, TET1, TET3 | KDM4E 231/4885GAA 536/4885HSD17B10 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.