Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 8/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29325261 | 0.93 | TXNRD1 (0.40) | TXNRD1MAPTMAPK1RAB9AIDO1 | |
| SCHEMBL27226473 | 0.87 | P2RX3 (0.36) | TXNRD1MAOAMAOBMAPTMGMT | |
| SCHEMBL27226444 | 0.86 | TXNRD1 (0.39) | TXNRD1MAOAMAOBMAPTNPC1 | |
| SCHEMBL27226601 | 0.83 | MAPT (0.43) | TXNRD1MAPTNPC1NFKB1MAPK1 | |
| SCHEMBL27226314 | 0.83 | MGMT (0.36) | MAPTMGMTNPC1NFKB1MAPK1 | |
| SCHEMBL27226976 | 0.79 | ABCG2 (0.35) | MAPTMGMTNPC1NFKB1MAPK1 | |
| SCHEMBL27226688 | 0.78 | MAPT (0.44) | MAPTMAPK1MEN1CYP1A2CYP2C9 | |
| SCHEMBL30815326 | 0.77 | ABCG2 (0.40) | MAPTNPC1NFKB1MAPK1RAB9A | |
| SCHEMBL27226818 | 0.77 | ABCG2 (0.40) | MAPTNPC1NFKB1MAPK1RAB9A | |
| SCHEMBL27226638 | 0.76 | BRD4 (0.32) | MAOAHSF1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594318-A1 | AKT1 MODULATORS | Alterome Therapeutics, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073371-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |