Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970186 | 0.82 | AHR (0.35) | AHRSYKP2RX7 | |
| SCHEMBL22344982 | 0.81 | — | — | |
| SCHEMBL31099577 | 0.81 | CDK8 (0.36) | AHRSYKP2RX7 | |
| SCHEMBL1973298 | 0.81 | AHR (0.34) | AHRSYKP2RX7 | |
| SCHEMBL25250074 | 0.72 | KIF11 (0.43) | SYK | |
| SCHEMBL10178037 | 0.70 | — | — | |
| SCHEMBL316640 | 0.70 | — | — | |
| SCHEMBL4083093 | 0.69 | — | — | |
| SCHEMBL16503647 | 0.69 | — | — | |
| SCHEMBL14151135 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |