SCHEMBL30818669

SCHEMBL30818669

c1ccc(N2CC(CCNc3cc(N4CCOCC4)ncn3)C2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CB P42338 2/20 0.63
NPC1 O15118 5/20 0.52
ALDH1A1 P00352 2/20 0.52
ATM Q13315 1/20 0.52
RAB9A P51151 5/20 0.49
HRH4 Q9H3N8 3/20 0.46
EGFR P00533 2/20 0.45
ERBB3 P21860 2/20 0.45
HSD17B10 Q99714 2/20 0.45
TP53 P04637 1/20 0.45
RECQL P46063 1/20 0.45
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
KMT2A Q03164 1/20 0.44
ABL1 P00519 1/20 0.42
BCR P11274 1/20 0.42
PRKDC P78527 1/20 0.42
MAPK1 P28482 1/20 0.41
HRH2 P25021 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30818762 0.93 PIK3CB (0.59) PIK3CBNPC1ALDH1A1ATMRAB9A
SCHEMBL30818629 0.89 PIK3CB (0.65) PIK3CBNPC1ALDH1A1ATMRAB9A
SCHEMBL30818599 0.83 PIK3CB (0.58) PIK3CBNPC1ALDH1A1ATMRAB9A
SCHEMBL30818959 0.81 PIK3CB (0.55) PIK3CBNPC1ALDH1A1ATMRAB9A
SCHEMBL30818713 0.81 PIK3CB (0.64) PIK3CBNPC1ALDH1A1ATMRAB9A
SCHEMBL30818696 0.78 PIK3CB (0.57) PIK3CBNPC1ALDH1A1ATMRAB9A
SCHEMBL5029684 0.77 PIK3CB (1.00) PIK3CBNPC1ALDH1A1ATMRAB9A
SCHEMBL30818772 0.77 PIK3CB (0.58) PIK3CBNPC1ALDH1A1ATMRAB9A
SCHEMBL5031512 0.76 PIK3CB (0.62) PIK3CBNPC1ALDH1A1ATMRAB9A
SCHEMBL30818958 0.76 PIK3CB (0.57) PIK3CBNPC1ALDH1A1ATMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587435-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS Cullgen (Shanghai), Inc. (CN) 2025-07-23 EP disclosed
WO-2024056077-A1 MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS CULLGEN (SHANGHAI) , INC. (CN) 2024-03-21 WO disclosed