Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 11/20 | 1.00 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.73 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | JAK1 | P23458 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029686 | 0.89 | PIK3CB (0.80) | PIK3CBHRH4NPC1ALDH1A1ACHE | |
| SCHEMBL4896185 | 0.83 | HRH4 (0.75) | PIK3CBHRH4NPC1ACHETSHR | |
| SCHEMBL27330852 | 0.80 | ABL1 (0.66) | PIK3CBNPC1ALDH1A1ATMHTT | |
| SCHEMBL30818629 | 0.79 | PIK3CB (0.65) | PIK3CBHRH4NPC1ALDH1A1ATM | |
| SCHEMBL30818713 | 0.78 | PIK3CB (0.64) | PIK3CBHRH4NPC1ALDH1A1ATM | |
| SCHEMBL30818669 | 0.77 | PIK3CB (0.63) | PIK3CBHRH4NPC1ALDH1A1ATM | |
| SCHEMBL14005278 | 0.77 | HRH4 (0.73) | PIK3CBHRH4ALDH1A1ACHETSHR | |
| SCHEMBL1774199 | 0.77 | HRH4 (0.66) | PIK3CBHRH4ALDH1A1TSHR | |
| SCHEMBL5031512 | 0.77 | PIK3CB (0.62) | PIK3CBHRH4NPC1ALDH1A1ATM | |
| SCHEMBL14005277 | 0.77 | HRH4 (0.65) | PIK3CBHRH4NPC1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101438288-A | Regulation of phosphoryl transferase activity of glutamine synthetase | CSIR CORP (ZA) | 2009-05-20 | — | — | CN | disclosed |
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |