Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30818669 | 0.81 | PIK3CB (0.63) | PIK3CBHRH4HRH3HRH2EGFR | |
| SCHEMBL5031512 | 0.79 | PIK3CB (0.62) | PIK3CBHRH4HRH3HRH2EGFR | |
| SCHEMBL30818762 | 0.79 | PIK3CB (0.59) | PIK3CBHRH4EGFRERBB3NPC1 | |
| SCHEMBL30818599 | 0.78 | PIK3CB (0.58) | PIK3CBHRH4EGFRERBB3NPC1 | |
| SCHEMBL30819005 | 0.74 | PIK3CB (0.51) | PIK3CBHRH4HRH3HRH2EGFR | |
| SCHEMBL30818623 | 0.74 | PIK3CB (0.50) | PIK3CBHRH4HRH3HRH2EGFR | |
| SCHEMBL4752569 | 0.73 | HRH4 (0.70) | PIK3CBHRH4HRH3HRH2ALDH1A1 | |
| SCHEMBL30818752 | 0.72 | HRH4 (0.49) | PIK3CBHRH4HRH3HRH2EGFR | |
| SCHEMBL30818781 | 0.71 | PIK3CB (0.53) | PIK3CBHRH4HRH3EGFRERBB3 | |
| SCHEMBL30818629 | 0.71 | PIK3CB (0.65) | PIK3CBHRH4EGFRERBB3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587435-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024056077-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2024-03-21 | — | — | WO | disclosed |