Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24776296 | 0.81 | MAPT (0.47) | MEN1NPC1RAB9AKMT2ACYP2D6 | |
| SCHEMBL31283928 | 0.81 | MAPT (0.47) | MEN1NPC1RAB9AKMT2ACYP2D6 | |
| SCHEMBL30819013 | 0.77 | HRH3 (0.40) | HRH3RAB9AKMT2AHTR1ADRD2 | |
| SCHEMBL26786048 | 0.67 | KDM4E (0.42) | MEN1KMT2ACYP2D6 | |
| SCHEMBL26649271 | 0.67 | PDE10A (0.32) | — | |
| SCHEMBL4766526 | 0.67 | HTT (0.42) | HTTCYP2D6 | |
| SCHEMBL4772199 | 0.66 | KMT2A (0.54) | HRH3MEN1KMT2AHTTCYP2D6 | |
| SCHEMBL30819029 | 0.65 | HTR3E (0.68) | HRH3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL15260204 | 0.64 | HRH3 (0.51) | HRH3 | |
| SCHEMBL6888086 | 0.64 | HRH3 (0.58) | HRH3NPC1RAB9AHTTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587435-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024056077-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2024-03-21 | — | — | WO | disclosed |