Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 8/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091592 | 0.97 | ADORA1 (0.40) | ADORA1AURKAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3086911 | 0.83 | ADORA1 (0.38) | ADORA1AURKAKDM4EALDH1A1GAA | |
| SCHEMBL3099226 | 0.83 | MEN1 (0.51) | ALDH1A1GAAHPGDMAPTMEN1 | |
| SCHEMBL3095689 | 0.80 | MEN1 (0.51) | ALDH1A1GAAHPGDMAPTMEN1 | |
| SCHEMBL3098350 | 0.80 | ADORA1 (0.41) | ADORA1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL3649435 | 0.80 | ALDH1A1 (0.38) | ADORA1AURKAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3095668 | 0.76 | ADORA1 (0.46) | ADORA1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL3087584 | 0.76 | MAPT (0.52) | ALDH1A1GAAHPGDMAPTMEN1 | |
| SCHEMBL3090523 | 0.75 | MAPT (0.49) | ALDH1A1GAAHPGDMAPTMEN1 | |
| SCHEMBL3099045 | 0.73 | NPC1 (0.39) | ADORA1KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202882-B2 | 5-cyanothienopyridines for the treatment of tumours | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20100234369-A1 | 5-CYANOTHIENOPYRIDINES FOR THE TREATMENT OF TUMOURS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234369-A1 | 5-CYANOTHIENOPYRIDINES FOR THE TREATMENT OF TUMOURS | TGFBR1, TGFBR2, ACVR1 | ADORA1 106/4885AURKA 484/4885KDM4E 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.