Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | BCR | P11274 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30818936 | 0.84 | JAK3 (0.46) | JAK3KDM4EPIK3CAPIK3CD | |
| SCHEMBL30818954 | 0.83 | KMO (0.50) | JAK3HTTKDM4EPOLBPIK3CA | |
| SCHEMBL2442888 | 0.82 | PIK3CA (0.62) | PIK3CAPIK3R1 | |
| SCHEMBL30818736 | 0.78 | JAK3 (0.49) | JAK3KDM4EPOLBBTK | |
| SCHEMBL2442130 | 0.78 | PIK3CD (0.69) | PIK3CAPIK3CDPIK3CBPIK3R1PIK3CG | |
| SCHEMBL30818898 | 0.77 | KMO (0.49) | JAK3HTTKDM4EPIK3CABTK | |
| SCHEMBL30818738 | 0.74 | JAK3 (0.46) | JAK3KDM4EPIK3CABTKKMO | |
| SCHEMBL16238117 | 0.73 | PIK3CA (0.56) | HTTKDM4EPOLBPIK3CAPIK3CD | |
| SCHEMBL30818858 | 0.72 | JAK3 (0.41) | JAK3KDM4EPOLBBTKKMO | |
| SCHEMBL2520544 | 0.72 | PIK3CB (0.39) | HTTPIK3CAPIK3CDPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587435-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024056077-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS AND DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2024-03-21 | — | — | WO | disclosed |