Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480758 | 0.98 | DNM1 (0.54) | DNM1LMNASLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL2484450 | 0.96 | DNM1 (0.52) | DNM1LMNASLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL2481683 | 0.96 | DNM1 (0.52) | DNM1LMNASLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL2485186 | 0.96 | DNM1 (0.52) | DNM1LMNASLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL2480274 | 0.96 | DNM1 (0.52) | DNM1LMNASLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL30937779 | 0.93 | DNM1 (0.52) | DNM1LMNASLC22A1ALDH1A1TP53 | |
| SCHEMBL23035066 | 0.89 | SLC22A1 (0.50) | DNM1LMNASLC22A1ALDH1A1TP53 | |
| SCHEMBL29393461 | 0.89 | SLC22A1 (0.50) | DNM1LMNASLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL2480151 | 0.87 | LMNA (0.49) | DNM1LMNASLC22A1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL2477272 | 0.87 | LMNA (0.49) | DNM1LMNASLC22A1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874256-B | Organosilicon quaternary ammonium salt biguanide salt material, preparation method and antibacterial application | 北京百灵威科技有限公司 | 2024-04-05 | — | — | CN | disclosed |