Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 19/20 | 1.00 |
| ▸ | AKR1C1 | Q04828 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011206 | 1.00 | AKR1C3 (1.00) | AKR1C3AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL14943437 | 0.88 | AKR1C3 (0.79) | AKR1C3AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL3280649 | 0.85 | AKR1C3 (0.76) | AKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL4239496 | 0.85 | AKR1C3 (0.76) | AKR1C3AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL12401136 | 0.85 | AKR1C3 (0.74) | AKR1C3AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL21067755 | 0.83 | PPARG (1.00) | AKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL693455 | 0.83 | KMT2A (1.00) | AKR1C3AKR1C1ALDH1A1MEN1KMT2A | |
| Thiophene Carboxylic Acid SCHEMBL29135076 | 0.82 | AKR1C3 (0.77) | AKR1C3AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL3287776 | 0.79 | AKR1C3 (0.66) | AKR1C3AKR1C1 | |
| SCHEMBL663840 | 0.79 | AKR1C3 (1.00) | AKR1C3AKR1C1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946126-A | Camptothecin derivative, composition containing derivative and application of camptothecin derivative | 中国药科大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-112961916-B | AKR1C3 as biological marker for liver cancer prognosis and application thereof | 上海市肿瘤研究所 | 2024-03-12 | — | — | CN | disclosed |