Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 17/20 | 0.77 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011206 | 0.82 | AKR1C3 (1.00) | AKR1C3AKR1C1MEN1KMT2AALDH1A1 | |
| SCHEMBL30819658 | 0.82 | AKR1C3 (1.00) | AKR1C3AKR1C1MEN1KMT2AALDH1A1 | |
| Thiophene Carboxylic Acid SCHEMBL29135074 | 0.81 | AKR1C3 (0.70) | AKR1C3AKR1C1MEN1KMT2AALDH1A1 | |
| SCHEMBL14943437 | 0.76 | AKR1C3 (0.79) | AKR1C3AKR1C1MEN1KMT2APPARG | |
| Carbamic Acid SCHEMBL27693825 | 0.75 | AKR1C3 (0.60) | AKR1C3AKR1C1MEN1KMT2AALDH1A1 | |
| SCHEMBL23081190 | 0.75 | AKR1C3 (0.78) | AKR1C3AKR1C1MEN1KMT2AALDH1A1 | |
| SCHEMBL12401136 | 0.73 | AKR1C3 (0.74) | AKR1C3AKR1C1MEN1KMT2APPARG | |
| SCHEMBL21067755 | 0.72 | PPARG (1.00) | AKR1C3AKR1C1MEN1KMT2APPARG | |
| SCHEMBL29134720 | 0.72 | NR3C1 (0.61) | AKR1C3AKR1C1ALDH1A1LMNAMAPT | |
| SCHEMBL693455 | 0.71 | KMT2A (1.00) | AKR1C3AKR1C1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117298108-A | Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof | 浙江师范大学 | 2023-12-29 | — | — | CN | disclosed |