Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2993694 | 1.00 | CCR2 (0.83) | CCR2CYP2D6 | |
| SCHEMBL2993760 | 0.97 | CCR2 (0.88) | CCR2CYP2D6 | |
| SCHEMBL2988924 | 0.97 | CCR2 (0.88) | CCR2CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL2985848 | 0.94 | CCR2 (0.94) | CCR2CYP2D6 | |
| SCHEMBL2985948 | 0.91 | CCR2 (1.00) | CCR2CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL2986719 | 0.89 | CCR2 (0.84) | CCR2CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL2988355 | 0.87 | CCR2 (0.72) | CCR2CYP2D6 | |
| SCHEMBL2987213 | 0.87 | CCR2 (0.88) | CCR2 | |
| Trifluoroacetic Acid SCHEMBL2994789 | 0.87 | CCR2 (0.68) | CCR2 | |
| Trifluoroacetic Acid SCHEMBL2994783 | 0.87 | CCR2 (0.68) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7776884-B2 | Cyclic derivatives as modulators of chemokine receptors activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-08-17 | — | — | US | disclosed |
| US-7087604-B2 | Cyclic derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-08-08 | — | — | US | disclosed |
| US-20060135503-A1 | Cyclic derivatives as modulators of chemokine receptors activity | CHERNEY ROBERT J | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135503-A1 | Cyclic derivatives as modulators of chemokine receptors activity | CCL11, CCR1, CCL2 | CCR2 10/4885CYP2D6 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.