Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29164630 | 1.00 | L3MBTL1 (0.43) | L3MBTL1MEN1KMT2ABRD4TAS1R3 | |
| SCHEMBL29164555 | 0.90 | L3MBTL1 (0.43) | L3MBTL1MEN1KMT2ABRD4TAS1R3 | |
| SCHEMBL706559 | 0.79 | MEN1 (0.63) | L3MBTL1MEN1KMT2ARAB9AJAK2 | |
| SCHEMBL29164565 | 0.78 | MEN1 (0.51) | L3MBTL1MEN1KMT2ARAB9AJAK2 | |
| SCHEMBL754986 | 0.76 | RAB9A (0.52) | L3MBTL1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30822730 | 0.76 | PDE10A (0.51) | KMT2ATAS1R3TAS1R1TAS1R2SORT1 | |
| SCHEMBL29164864 | 0.76 | PDE10A (0.51) | KMT2ATAS1R3TAS1R1TAS1R2SORT1 | |
| SCHEMBL29164538 | 0.76 | TYK2 (0.57) | L3MBTL1KMT2ARAB9APTGESJAK2 | |
| SCHEMBL29164888 | 0.73 | TYK2 (0.42) | L3MBTL1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL3418472 | 0.72 | RXFP1 (0.57) | L3MBTL1MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659001-A | Aminopyrimidine derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-03-08 | — | — | CN | disclosed |