SCHEMBL30822754

SCHEMBL30822754

Nc1ncnc2c1ncn2[C@@]1(S)C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 2/20 0.56
ADORA3 P0DMS8 6/20 0.54
ADORA2A P29274 4/20 0.54
PI4KA P42356 3/20 0.51
PI4K2B Q8TCG2 3/20 0.51
PI4K2A Q9BTU6 3/20 0.51
PI4KB Q9UBF8 3/20 0.51
DPP4 P27487 1/20 0.51
MEN1 O00255 1/20 0.51
MAP3K7 O43318 1/20 0.51
SLC28A2 O43868 1/20 0.51
GAPDH P04406 1/20 0.51
MAPK1 P28482 1/20 0.51
ADORA2B P29275 1/20 0.51
ADORA1 P30542 1/20 0.51
STAT6 P42226 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
DOT1L Q8TEK3 1/20 0.51
SLC29A1 Q99808 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2335292 0.85 SLC28A1 (0.57) SLC28A1ADORA3ADORA2API4KAPI4K2B
SCHEMBL29362292 0.85 SLC28A1 (0.57) SLC28A1ADORA3ADORA2API4KAPI4K2B
SCHEMBL9956204 0.85 SLC28A1 (0.57) SLC28A1ADORA3ADORA2API4KAPI4K2B
SCHEMBL6756465 0.85 SLC28A1 (0.57) SLC28A1ADORA3ADORA2API4KAPI4K2B
SCHEMBL29745935 0.84 SLC28A1 (0.56) SLC28A1ADORA3ADORA2API4KAPI4K2B
SCHEMBL439243 0.84 SLC28A1 (0.56) SLC28A1ADORA3ADORA2API4KAPI4K2B
SCHEMBL3466617 0.84 SLC28A1 (0.56) SLC28A1ADORA3ADORA2API4KAPI4K2B
SCHEMBL29459696 0.84 SLC28A1 (0.56) SLC28A1ADORA3ADORA2API4KAPI4K2B
SCHEMBL66047 0.84 SLC28A1 (0.56) SLC28A1ADORA3ADORA2API4KAPI4K2B
SCHEMBL29799646 0.84 SLC28A1 (0.56) SLC28A1ADORA3ADORA2API4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924393-A Monomer of 3' -mercapto nucleoside analogue and its synthesis process 天津兴博润生物制药有限公司 2024-04-26 CN disclosed