Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23302280 | 0.81 | ADRA2A (0.45) | POLBTDP1ALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL23302378 | 0.79 | ADRA2A (0.47) | POLBTDP1ALDH1A1CA12CA1 | |
| SCHEMBL11759344 | 0.76 | MEN1 (0.41) | POLBTDP1ALDH1A1CA12CA1 | |
| SCHEMBL7349 | 0.75 | ALDH1A1 (0.47) | POLBTDP1ALDH1A1CA12CA1 | |
| SCHEMBL29573636 | 0.75 | ALDH1A1 (0.47) | POLBTDP1ALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL29573589 | 0.73 | ALDH1A1 (0.46) | POLBTDP1ALDH1A1CA12CA1 | |
| Hydrochloric Acid SCHEMBL1843712 | 0.73 | ALDH1A1 (0.46) | POLBTDP1ALDH1A1CA12CA1 | |
| SCHEMBL18904808 | 0.72 | MEN1 (0.60) | POLBTDP1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL27993335 | 0.70 | CETP (0.39) | POLBTDP1ALDH1A1CA12CA1 | |
| SCHEMBL1537798 | 0.69 | ALDH1A1 (0.52) | POLBTDP1ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024041586-A1 | PRODRUG OF JAK KINASE INHIBITOR | 启元生物(杭州)有限公司 | 2024-02-29 | — | — | WO | disclosed |